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TiO 2 ‐Supported Re as a General and Chemoselective Heterogeneous Catalyst for Hydrogenation of Carboxylic Acids to Alcohols
Author(s) -
Toyao Takashi,
Siddiki S. M. A. Hakim,
Touchy Abeda S.,
Onodera Wataru,
Kon Kenichi,
Morita Yoshitsugu,
Kamachi Takashi,
Yoshizawa Kazunari,
Shimizu Kenichi
Publication year - 2017
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201604762
Subject(s) - catalysis , yield (engineering) , chemistry , substrate (aquarium) , organic chemistry , transition metal , heterogeneous catalysis , carboxylic acid , materials science , oceanography , metallurgy , geology
TiO 2 ‐supported Re, Re/TiO 2 , was found to promote selective hydrogenation of carboxylic acids having aromatic and aliphatic moieties to the corresponding alcohols. Re/TiO 2 showed superior results compared to other transition‐metal‐loaded TiO 2 and supported Re catalysts for selective hydrogenation of 3‐phenylpropionic acid. 3‐phenylpropanol was produced in 97 % yield under mild conditions (5 MPa H 2 at 140 °C). Contrary to typical heterogeneous catalysts, Re/TiO 2 does not lead to the formation of dearomatized byproducts. The catalyst is recyclable and shows a wide substrate scope in the synthesis of alcohols (22 examples; up to 97 % isolated yield).