Premium
Pd‐Catalyzed Carboamination of Alkylidenecyclopropanes: Synthesis of Congested Pyrrolidines and Piperidines
Author(s) -
Lazzara Phillip R.,
Fitzpatrick Keegan P.,
Eichman Chad C.
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201604077
Subject(s) - pyrrolidine , piperidine , catalysis , chemistry , organic chemistry , combinatorial chemistry
The synthesis of densely functionalized N‐heterocycles is an ongoing challenge in chemical synthesis. Herein, we report an efficient method for the construction of pyrrolidine and piperidine scaffolds using a palladium‐catalyzed carboamination of alkylidenecyclopropanes.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom