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Detoxification of Chemical Warfare Agents Using a Zr 6 ‐Based Metal–Organic Framework/Polymer Mixture
Author(s) -
Moon SuYoung,
Proussaloglou Emmanuel,
Peterson Gregory W.,
DeCoste Jared B.,
Hall Morgan G.,
Howarth Ashlee J.,
Hupp Joseph T.,
Farha Omar K.
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201603976
Subject(s) - nerve agent , hydrolysis , metal organic framework , zirconium , buffer (optical fiber) , chemical warfare agents , metal , chemical stability , chemistry , polymer , chemical warfare , catalysis , chemical engineering , materials science , inorganic chemistry , organic chemistry , computer science , adsorption , telecommunications , law , biochemical engineering , political science , engineering , acetylcholinesterase , enzyme
Owing to their high surface area, periodic distribution of metal sites, and water stability, zirconium‐based metal–organic frameworks (Zr 6 ‐MOFs) have shown promising activity for the hydrolysis of nerve agents GD and VX, as well as the simulant, dimethyl 4‐nitrophenylphosphate (DMNP), in buffered solutions. A hurdle to using MOFs for this application is the current need for a buffer solution. Here the destruction of the simulant DMNP, as well as the chemical warfare agents (GD and VX) through hydrolysis using a MOF catalyst mixed with a non‐volatile, water‐insoluble, heterogeneous buffer is reported. The hydrolysis of the simulant and nerve agents in the presence of the heterogeneous buffer was fast and effective.

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