Premium
Oxidative Annulation of Arenecarboxylic and Acrylic Acids with Alkynes under Ambient Conditions Catalyzed by an Electron‐Deficient Rhodium(III) Complex
Author(s) -
Kudo Eiji,
Shibata Yu,
Yamazaki Mutsumi,
Masutomi Koji,
Miyauchi Yuta,
Fukui Miho,
Sugiyama Haruki,
Uekusa Hidehiro,
Satoh Tetsuya,
Miura Masahiro,
Tanaka Ken
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201603499
Subject(s) - annulation , rhodium , oxidative phosphorylation , isocoumarins , catalysis , chemistry , medicinal chemistry , organic chemistry , photochemistry , biochemistry
Abstract It has been established that an electron‐deficient Cp E rhodium(III) complex catalyzes the oxidative [4+2] annulation of substituted arenecarboxylic and acrylic acids with alkynes under ambient conditions (at RT–40 °C, under air) without using excess amounts of substrates to produce the corresponding substituted isocoumarins and α‐pyrones in high yields. Minor modification of reaction conditions depending on the coordination ability of alkynes realized the high efficiency.