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Readily Accessible and Predictable Naphthalene‐Based Two‐Photon Fluorophore with Full Visible‐Color Coverage
Author(s) -
Koo Ja Young,
Heo Cheol Ho,
Shin YoungHee,
Kim Dahahm,
Lim Chang Su,
Cho Bong Rae,
Kim Hwan Myung,
Park Seung Bum
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201603496
Subject(s) - fluorophore , fluorescence , wavelength , two photon excitation microscopy , photon , excitation wavelength , excitation , optoelectronics , materials science , visible spectrum , optics , chemistry , physics , quantum mechanics
Herein we report 22 acedan‐derived, two‐photon fluorophores with synthetic feasibility and full coverage of visible wavelength emission. The emission wavelengths were predicted by computational analysis, which enabled us to visualize multicolor images by two‐photon excitation with single wavelength, and to design a turn‐on, two‐photon fluorescence sensor for endogenous H 2 O 2 in Raw 264.7 macrophage and rat brain hippocampus ex vivo.