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Visible‐Light‐Induced Trifluoromethylation of Isonitrile‐Substituted Methylenecyclopropanes: Facile Access to 6‐(Trifluoromethyl)‐7,8‐Dihydrobenzo[ k ]phenanthridine Derivatives
Author(s) -
Yuan YuChao,
Liu HouLu,
Hu XuBo,
Wei Yin,
Shi Min
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201602920
Subject(s) - phenanthridine , trifluoromethylation , trifluoromethyl , chemistry , visible spectrum , photochemistry , tandem , ring (chemistry) , medicinal chemistry , stereochemistry , organic chemistry , materials science , alkyl , optoelectronics , composite material
A new visible‐light‐induced trifluoromethylation of isonitrile‐substituted methylenecyclopropanes is developed. A range of substituted 6‐(trifluoromethyl)‐7,8‐dihydrobenzo[ k ]phenanthridine derivatives are readily furnished by this newly developed tandem reaction with moderate to good yields. This reaction allows the direct formation of two six‐membered rings and three new C−C bonds, including the C−CF 3 bond, under visible light irradiation.