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Inside Back Cover: A Major Advance in the Synthesis of Fluoroalkyl Pyrazoles: Tuneable Regioselectivity and Broad Substitution Patterns (Chem. Eur. J. 32/2016)
Author(s) -
Schmitt Etienne,
Panossian Armen,
Vors JeanPierre,
Funke Christian,
Lui Norbert,
Pazenok Sergiy,
Leroux Frédéric R.
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201602703
Subject(s) - regioselectivity , hydrazine (antidepressant) , cover (algebra) , reactivity (psychology) , substitution (logic) , combinatorial chemistry , chemistry , variety (cybernetics) , stereochemistry , computer science , organic chemistry , engineering , artificial intelligence , catalysis , biochemistry , medicine , alternative medicine , pathology , programming language , mechanical engineering
Fluoroalkyl pyrazoles , which are key building blocks in agrochemistry and promising candidates in life‐science‐oriented research, have shown much potential in accessing a variety of bis(fluoroalkyl)pyrazoles with tunable regioselectivity of the hydrazine addition, via two intermediates of opposed reactivity. The two strategies are represented by one slingshot aiming at two different targets, with a background of crops, forests, and laboratory activities. More information can be found in the Full Paper by S. Pazenok, F. R. Leroux et al. on page 11239.