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Engineering the Ionic Self‐Assembly of Polyoxometalates and Facial‐Like Peptides
Author(s) -
Li Jingfang,
Li Xiaodong,
Xu Jing,
Wang Yang,
Wu Lixin,
Wang Yanqiu,
Wang Liyan,
Lee Myongsoo,
Li Wen
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201602449
Subject(s) - random coil , circular dichroism , self assembly , ionic bonding , hydrogen bond , chemistry , nanostructure , cationic polymerization , intermolecular force , peptide , crystallography , protonation , intramolecular force , molecule , hydrophobic effect , nanotechnology , materials science , stereochemistry , polymer chemistry , organic chemistry , ion , biochemistry
The self‐assembly behavior of polyoxometalates (PMs) and facial‐like cationic peptides carrying lysine residues were systematically investigated. Circular dichroism and UV/Vis spectra demonstrated that the multivalent electrostatic attractions between polyanionic PMs and short peptides with protonated lysine residues initiated the conformational transition of peptide molecules from random‐coil to β‐sheet state, and subsequently the co‐assembly. TEM and atomic force microscopy (AFM) measurements showed that uniform nanofibers formed with decreasing size of the PMs or increasing the intermolecular forces of the peptides, such as through hydrogen‐bonding, hydrophobic, and/or π–π interactions. Additionally, the stability of the nanostructures can be improved by rational suppression of the electrostatic repulsion of the shell peptides covering the surface of the nanostructures. These results provide new insight into understanding the ionic self‐assembly of peptides and PMs and controlling their final morphology.