Premium
Hyperpolarization of Nitrogen‐15 Schiff Bases by Reversible Exchange Catalysis with para ‐Hydrogen
Author(s) -
Logan Angus W. J.,
Theis Thomas,
Colell Johannes F. P.,
Warren Warren S.,
Malcolmson Steven J.
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201602393
Subject(s) - catalysis , nitrogen , chemistry , hydrogen , hyperpolarization (physics) , inorganic chemistry , photochemistry , organic chemistry , nuclear magnetic resonance spectroscopy
NMR with thermal polarization requires relatively concentrated samples, particularly for nuclei with low abundance and low gyromagnetic ratios, such as 15 N. We expand the substrate scope of SABRE, a recently introduced hyperpolarization method, to allow access to 15 N‐enriched Schiff bases. These substrates show fractional 15 N polarization levels of up to 2 % while having only minimal 1 H enhancements.