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A Selective Rh I ‐Catalyzed Substrate‐Controlled C−C Bond Activation of Benzyl Sulfonamide/Alcohol‐Tethered Alkylidenecyclopropanes
Author(s) -
Chen Kai,
Liu JiaXin,
Tang XiangYing,
Shi Min
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201602366
Subject(s) - azepine , sulfonamide , benzyl alcohol , chemistry , catalysis , substrate (aquarium) , rhodium , alcohol , conjugated system , medicinal chemistry , stereochemistry , organic chemistry , oceanography , polymer , geology
Abstract Benzyl sulfonamide/alcohol‐tethered alkylidenecyclopropanes undergo a rhodium‐catalyzed and substrate‐controlled selective C−C bond activation, producing three types of common organic structural units: benzo[c]azepine/oxepines, dihydronaphthalen‐1‐amines, and conjugated dienes. Epoxidation and aromatization of these products to construct two useful compounds have also been achieved.