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Recent Advances in Gold‐Catalyzed Intermolecular Aryl C−H Functionalization
Author(s) -
Kramer Søren
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201602316
Subject(s) - surface modification , intermolecular force , catalysis , regioselectivity , aryl , combinatorial chemistry , homogeneous , chemistry , nanotechnology , homogeneous catalysis , organic chemistry , materials science , molecule , mathematics , alkyl , combinatorics
The direct and selective functionalization of C−H bonds offers a powerful opportunity for greener and shorter routes to valuable chemicals. While still in its infancy, research exploiting the unique features of gold catalysis for the functionalization of aryl C−H bonds has demonstrated great potential for facile regioselective decoration of (hetero)arenes. Particularly within the last five years, a more general strategy for utilizing oxidative gold catalysis has emanated including an improved understanding of the underlying mechanistic pathways. To encourage and facilitate further research in intermolecular C−H functionalization of arenes with homogeneous gold catalysis, this Minireview critically presents the transformations and mechanistic data available within this field.