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Synthesis of ( E )‐4‐Bromo‐3‐methoxybut‐3‐en‐2‐one, the Key Fragment in the Polyhydroxylated Chain Common to Oscillariolide and Phormidolides A–C
Author(s) -
Gil Alejandro,
LamarianoMerketegi Janire,
Lorente Adriana,
Albericio Fernando,
Álvarez Mercedes
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201601578
Subject(s) - moiety , fragment (logic) , stereochemistry , key (lock) , chemistry , cover (algebra) , computer science , engineering , computer security , algorithm , mechanical engineering
Abstract Invited for the cover of this issue is the group of Mercedes Álvarez at the University of Barcelona. The image depicts the Álvarez group′s effort to successfully “fish” an efficient strategy for the synthesis of the bromomethoxydiene (BMD) moiety present in marine natural products such as phormidolides and oscillariolides. Read the full text of the article at 10.1002/chem.201600770.