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Cover Picture: Ring Opening of Donor–Acceptor Cyclopropanes with the Azide Ion: A Tool for Construction of N‐Heterocycles (Chem. Eur. J. 13/2015)
Author(s) -
Ivanov Konstantin L.,
Villemson Elena V.,
Budynina Ekaterina M.,
Ivanova Olga A.,
Trushkov Igor V.,
Melnikov Mikhail Ya.
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201590047
Subject(s) - kaleidoscope , regioselectivity , stereospecificity , azide , ring (chemistry) , combinatorial chemistry , acceptor , cycloaddition , nanotechnology , chemistry , materials science , computer science , organic chemistry , physics , catalysis , programming language , condensed matter physics
A kaleidoscope of synthetic opportunities is provided by a new family of densely functionalized organic building blocks produced by means of one simple operation; regioselective and stereospecific ring opening of donor–acceptor cyclopropanes with the azide ion. The tolerance of functionalities versus their strategic placement combined with the ability to undergo selective modification allow these building blocks to easily yield a great diversity of N ‐heterocycles of synthetic and biological relevance. For more details see the Full Paper by E. M. Budynina, I. V. Trushkov et al. on p. 4975 ff.