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Inside Cover: Insights into the Crystallisation Process from Anhydrous, Hydrated and Solvated Crystal Forms of Diatrizoic Acid (Chem. Eur. J. 3/2015)
Author(s) -
Fucke Katharina,
McIntyre Garry J.,
LeméeCailleau MarieHélène,
Wilkinson Clive,
Edwards Alison J.,
Howard Judith A. K.,
Steed Jonathan W.
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201590006
Subject(s) - anhydrous , solvation , crystal structure , crystallography , lattice energy , hydrogen bond , crystal (programming language) , crystallization , molecule , chemistry , crystal engineering , halogen bond , halogen , lattice (music) , materials science , supramolecular chemistry , chemical physics , organic chemistry , physics , computer science , programming language , alkyl , acoustics
The clinically used X‐ray contrast agent diatrizoic acid exhibits 14 crystal forms including hydrates and solvates. Structural investigations using neutron and X‐radiation in connection with crystal lattice energy calculations give insight into the strength and interplay of hydrogen and halogen bonding for stabilisation of the lattice. The conformation of the molecule and the crystal packing is directly influenced by the solvation of the crystal form. For more details, see the Full Paper by K. Fucke et al. on page 1036 ff.