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Inside Cover: Efficient Biomimetic Hydroxylation Catalysis with a Bis(pyrazolyl)imidazolylmethane Copper Peroxide Complex (Chem. Eur. J. 49/2015)
Author(s) -
Wilfer Claudia,
Liebhäuser Patricia,
Hoffmann Alexander,
Erdmann Hannes,
Grossmann Oleg,
Runtsch Leander,
Paffenholz Eva,
Schepper Rahel,
Dick Regina,
Bauer Matthias,
Dürr Maximilian,
IvanovićBurmazović Ivana,
HerresPawlis Sonja
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201584902
Subject(s) - hydroxylation , chemistry , peroxide , catalysis , tyrosinase , copper , ligand (biochemistry) , combinatorial chemistry , stereochemistry , cover (algebra) , polymer chemistry , organic chemistry , enzyme , receptor , biochemistry , mechanical engineering , engineering
A catalytic vortex producing quinones was realized by a (μ‐η 2 :η 2 )‐peroxo dicopper(II) core resembling the active centre of tyrosinase. This biomimetic species is stabilised by a new bis(pyrazolyl)imidazolylmethane ligand. Kinetic experiments show that this peroxide species mediates phenole hydroxylation with almost biological speed. This enhancement was achieved by exchanging a pyridinyl donor against the imidazolyl donor. For more details, see the Full Paper by S. Herres‐Pawlis and co‐workers on page 17639 ff.