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Inside Cover: Substrate‐Controlled Asymmetric Total Syntheses of Microcladallenes A, B, and C Based on the Proposed Structures (Chem. Eur. J. 45/2015)
Author(s) -
Sohn Teik,
Kim Deukjoon,
Paton Robert S.
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201584502
Subject(s) - stereocenter , cover (algebra) , rainbow , substrate (aquarium) , sequence (biology) , halogen , skeleton (computer programming) , stereochemistry , crystallography , combinatorics , materials science , chemistry , mathematics , physics , computer science , optics , enantioselective synthesis , engineering , organic chemistry , geology , mechanical engineering , biochemistry , alkyl , programming language , catalysis , oceanography
Substrate‐controlled asymmetric total syntheses of the proposed structures of microcladallenes A, B, and C have been accomplished. In their Full Paper on page 15988 ff. , D. Kim and co‐workers confirm the structures and absolute configurations of microcladallenes A and B, and demonstrate that the structure of microcladallene C must be revised. This structure is shown in the cover image and is the most challenging target of the three, containing four halogen atoms in its compact C‐15 skeleton. The rainbow color‐scheme and the size of the red stars indicate the sequence in which the stereogenic centers were introduced in the synthesis.