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Cover Picture: Source of Selectivity in Oxidative Cross‐Coupling of Aryls by Solvent Effect of 1,1,1,3,3,3‐Hexafluoropropan‐2‐ol (Chem. Eur. J. 35/2015)
Author(s) -
Elsler Bernd,
Wiebe Anton,
Schollmeyer Dieter,
Dyballa Katrin M.,
Franke Robert,
Waldvogel Siegfried R.
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201583501
Subject(s) - selectivity , chemistry , solvent , bimetallic strip , nucleophile , decoupling (probability) , solvent effects , oxidative coupling of methane , electrochemistry , combinatorial chemistry , photochemistry , catalysis , organic chemistry , electrode , control engineering , engineering
Precisely adjusted solvates. influence the oxidation potential of substrates for the electrochemical cross‐coupling of arenes. The solvent mixture based on 1,1,1,3,3,3‐hexafluoroisopropanol (HFIP) and MeOH gives rise to a decoupling of nucleophilicity from the oxidation potential. In their Full Paper on page 12321 ff. , S. R. Waldvogel and co‐authors rationalize the outstanding selectivity of the anodic cross‐coupling. This solvent effect explains also the selectivity previously found by HFIP mixtures.