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Frontispiece: Orienting Tetramolecular G‐Quadruplex Formation: The Quest for the Elusive RNA Antiparallel Quadruplex
Author(s) -
Mendoza Oscar,
Porrini Massimiliano,
Salgado Gilmar F.,
Gabelica Valérie,
Mergny JeanLouis
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201581862
Subject(s) - antiparallel (mathematics) , g quadruplex , duplex (building) , dna , supramolecular chemistry , rna , nanotechnology , chemistry , computational biology , biology , crystallography , physics , materials science , biochemistry , crystal structure , quantum mechanics , gene , magnetic field
G‐Quadruplexes Duplex DNA formation allows the predictable construction of nanomaterials with a large number of potential applications. Additionally, duplexes and quadruplexes may be combined to form predictable supramolecular structures. In their Full Paper on page 6732 ff. , J.‐L. Mergny et al. show how classical duplex DNA can guide the strand polarity of a quadruplex motif in a duplex–quadruplex substrate.