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Frontispiece: Matrix‐Free DNP‐Enhanced NMR Spectroscopy of Liposomes Using a Lipid‐Anchored Biradical
Author(s) -
FernándezdeAlba Carlos,
Takahashi Hiroki,
Richard Alexandre,
Chenavier Yves,
Dubois Lionel,
Maurel Vincent,
Lee Daniel,
Hediger Sabine,
De Paëpe Gaël
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201581261
Subject(s) - liposome , membrane , lipid bilayer , nuclear magnetic resonance spectroscopy , matrix (chemical analysis) , spectroscopy , chemistry , bilayer , materials science , combinatorial chemistry , nanotechnology , organic chemistry , physics , chromatography , biochemistry , quantum mechanics
Matrix‐Free DNP on Lipid Membranes Dynamic nuclear polarization (DNP) has been proven to be a powerful technique to enhance the sensitivity of solid‐state NMR. However, until now, there has been limited success in its application to synthetic membrane‐type systems. In their Communication on page 4512 ff. , G. De Paëpe et al. present an innovative approach based on system‐driven radical design in order to insert the polarizing agent inside a lipid bilayer. Combined with matrix‐free DNP, this strategy solves additive‐induced problems by releasing the need for a DNP‐compatible solvent.