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Frontispiece: High Impact of Uranyl Ions on Carrying–Releasing Oxygen Capability of Hemoglobin‐Based Blood Substitutes
Author(s) -
Duan Li,
Du Lili,
Jia Yi,
Liu Wenyuan,
Liu Zhichao,
Li Junbai
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201580261
Subject(s) - uranyl , adsorption , hemoglobin , chemical engineering , blood substitute , oxygen , nanoparticle , chemistry , microsphere , porosity , metal ions in aqueous solution , materials science , ion , layer (electronics) , nanotechnology , organic chemistry , engineering
Hemoglobin In their Full Paper on page 520 ff., J. Li et al. show how hemoglobin (Hb) microspheres fabricated by porous template covalent layer‐by‐layer assembly were utilized as artificial oxygen carriers: blood substitutes. Magnetic nanoparticles Fe 3 O 4 were loaded in porous CaCO 3 particles for magnetically assisted chemical separation. It was found that UO 2 2+ was highly loaded in the magnetic Hb microspheres, and they show that the presence of UO 2 2+ in vivo seriously destroys the structure and oxygen‐transport capability of Hb microspheres. In view of the high adsorption capacity of UO 2 2+ , the as‐assembled magnetic Hb microspheres can be considered as a novel, highly effective adsorbent for removing the metal toxins from radioactively contaminated bodies or from nuclear‐power reactor effluents before discharge into the environment.