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Expansion of the Concept of Nonlinear Effects in Catalytic Reactions Beyond Asymmetric Catalysis
Author(s) -
Pollice Robert,
Schnürch Michael
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201504970
Subject(s) - catalysis , enantiomer , enantioselective synthesis , nonlinear system , chirality (physics) , chemistry , mechanism (biology) , enantiomeric excess , computational chemistry , reaction mechanism , combinatorial chemistry , organic chemistry , physics , quantum mechanics , chiral symmetry breaking , nambu–jona lasinio model , quark
The observation and investigation of nonlinear effects in catalytic reactions provides valuable mechanistic insight. However, the applicability of this method was, until now, limited to molecules possessing chirality and therefore to asymmetric synthesis. The concept of nonlinear effects is expanded to catalytic reactions beyond asymmetric catalysis by using derivatives instead of enantiomers and by considering rates instead of enantiomeric excess. Additionally, its systematic application to investigate the mechanism of catalytic reactions is presented. By exceeding the limitation to asymmetric reactions, the study of nonlinear effects can become a general tool to elucidate reaction mechanisms.