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Rhodium(II)‐Catalyzed and Thermally Induced Intramolecular Migration of N ‐Sulfonyl‐1,2,3‐triazoles: New Approaches to 1,2‐Dihydroisoquinolines and 1‐Indanones
Author(s) -
Sun Run,
Jiang Yu,
Tang XiangYing,
Shi Min
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201504914
Subject(s) - sulfonyl , intramolecular force , rhodium , carbene , chemistry , alkoxy group , catalysis , medicinal chemistry , combinatorial chemistry , polymer chemistry , stereochemistry , organic chemistry , alkyl
New rhodium(II)‐catalyzed or thermally induced intramolecular alkoxy group migration of N ‐sulfonyl‐1,2,3‐triazoles has been developed, affording divergent synthesis of 1,2‐dihydroisoquinoline and 1‐indanone derivatives according to different conditions. N ‐Sulfonyl keteneimine is the key intermediate for the synthesis of dihydroisoquinoline, whereas the aza‐vinyl carbene intermediate results in the formation of 1‐indanone.