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Iridium(I) N‐Heterocyclic Carbene (NHC)/Phosphine Catalysts for Mild and Chemoselective Hydrogenation Processes
Author(s) -
Kerr William J.,
Mudd Richard J.,
Brown Jack A.
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201504825
Subject(s) - iridium , phosphine , carbene , catalysis , ligand (biochemistry) , selectivity , chemistry , combinatorial chemistry , organic chemistry , noyori asymmetric hydrogenation , ruthenium , biochemistry , receptor
The directed chemoselective hydrogenation of olefins has been established by using iridium(I) catalysts, which feature a tuned NHC/phosphine ligand combination. This selective reduction process has been demonstrated in a wide array of solvents, including more environmentally acceptable media, also allowing further refinement of hydrogenation selectivity.