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Thioamination of Alkenes with Hypervalent Iodine Reagents
Author(s) -
Mizar Pushpak,
Niebuhr Rebecca,
Hutchings Matthew,
Farooq Umar,
Wirth Thomas
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201504636
Subject(s) - hypervalent molecule , reagent , iodine , nucleophile , chemistry , sulfur , stereoselectivity , combinatorial chemistry , iodine compounds , organic chemistry , catalysis
An efficient thioamination of alkenes mediated by iodine(III) reagents is described. The use of different sulfur nucleophiles allows the flexible synthesis of 1,2‐aminothiols from alkenes. By employing chiral iodine(III) reagents, a stereoselective version of the thioamination protocol has also been developed.