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Trifluoromethylselenolation of Aryldiazonium Salts: A Mild and Convenient Copper‐Catalyzed Procedure for the Introduction of the SeCF 3 Group
Author(s) -
Nikolaienko Pavlo,
Rueping Magnus
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201504601
Subject(s) - reagent , chemistry , catalysis , combinatorial chemistry , potassium , copper , group (periodic table) , organic chemistry
Abstract The straightforward introduction of the trifluoromethylseleno group into aromatic and heteroaromatic compounds is accomplished by the utilization of readily available aryldiazonium tetrafluoroborates, potassium selenocyanate, and Ruppert–Prakash reagent. The reaction tolerates a wide range of aromatic and heteroaromatic diazonium salts and is also amenable to the synthesis of pentafluoroethyl selenoethers. Furthermore, the methodology can be applied directly starting from anilines.