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A New Approach for the Synthesis of Highly Substituted Aromatic Rings: The Alkyne‐Mediated Approach
Author(s) -
Parsons Philip J.,
Jones Daniel R.,
Padgham Alex C.,
Allen Lewis A. T.,
Penkett Clive S.,
Green Robert A.,
White Andrew J. P.
Publication year - 2016
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201504421
Subject(s) - alkyne , aromaticity , combinatorial chemistry , thermal decomposition , template , chemistry , organic chemistry , materials science , nanotechnology , catalysis , molecule
Pentasubstituted aromatic rings serve as templates for drug design and can be conveniently prepared by the thermolysis of suitably substituted alkynes under microwave conditions.