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Visible‐Light‐Induced Direct Photocatalytic Carboxylation of Indoles with CBr 4 /MeOH
Author(s) -
Yang QingQing,
Marchini Marianna,
Xiao WenJing,
Ceroni Paola,
Bandini Marco
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201503787
Subject(s) - carboxylation , photocatalysis , indole test , chemistry , surface modification , visible spectrum , photochemistry , combinatorial chemistry , methanol , reaction conditions , catalysis , organic chemistry , materials science , optoelectronics
Photocatalysis enables the cascade reactions of indoles and CBr 4 in MeOH through a C(sp 2 )H functionalization/methanolysis sequence. The title reaction provides an efficient access to indole 2‐ and 3‐carboxylates in a single operation (no preinstallation of protecting as well as directing groups was required) with good yields under mild reaction conditions.

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