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Cobalt(III)‐Catalyzed CH/NO Functionalizations: Isohypsic Access to Isoquinolines
Author(s) -
Wang Hui,
Koeller Julian,
Liu Weiping,
Ackermann Lutz
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201503624
Subject(s) - cobalt , catalysis , annulation , chemistry , combinatorial chemistry , stereochemistry , medicinal chemistry , organic chemistry
CH/NO functionalizations by cobalt(III) catalysis allowed the expedient synthesis of a broad range of isoquinolines. Thus, internal and challenging terminal alkynes proved to be viable substrates for an isohypsic annulation, which was shown to proceed by a facile CH cobaltation.
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