Premium
Transition‐Metal‐Free N ‐Arylation of Pyrazoles with Diaryliodonium Salts
Author(s) -
Gonda Zsombor,
Novák Zoltán
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201502995
Subject(s) - transition metal , chemistry , organic chemistry , catalysis
Abstract A new synthetic method was developed for the N ‐arylation of pyrazoles using diaryliodonium salts. The transformation does not require any transition‐metal catalyst and provides the desired N ‐arylpyrazoles rapidly under mild reaction condition in the presence of aqueous ammonia solution as a mild base without the use of inert atmosphere. The chemoselectivity of unsymmetric diaryliodonium salts was also explored with large number of examples.