Premium
A Convenient Palladium‐Catalyzed Carbonylative Suzuki Coupling of Aryl Halides with Formic Acid as the Carbon Monoxide Source
Author(s) -
Qi Xinxin,
Jiang LiBing,
Li HaoPeng,
Wu XiaoFeng
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201502943
Subject(s) - carbon monoxide , aryl , carbonylation , halide , palladium , formic acid , catalysis , chemistry , acetic anhydride , monoxide , suzuki reaction , acetic acid , organic chemistry , alkyl
A practical palladium‐catalyzed carbonylative Suzuki coupling of aryl halides under carbon monoxide gas‐free conditions has been developed. Here, formic acid was utilized as the carbon monoxide source for the first time with acetic anhydride as the additive. A variety of diarylketones were produced in moderate to excellent yields from the corresponding aryl halides and arylboronic acids.