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A Biphasic Mercury‐Ion Sensor: Exploiting Microfluidics to Make Simple Anilines Competitive Ligands
Author(s) -
Petzoldt Martin,
Eschenbaum Carsten,
Schwaebel S. Thimon,
Broedner Kerstin,
Lemmer Uli,
Hamburger Manuel,
Bunz Uwe H. F.
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201502736
Subject(s) - mercury (programming language) , microfluidics , analyte , conjugated system , nanotechnology , ion , chemistry , biosensor , polymer , competitive binding , materials science , combinatorial chemistry , chromatography , organic chemistry , computer science , programming language , biochemistry , receptor
Combining the molecular wire effect with a biphasic sensing approach (analyte in water, sensor‐dye in 2‐methyltetrahydrofuran) and a microfluidic flow setup leads to the construction of a mercury‐sensitive module. We so instantaneously detect Hg 2+ ions in water at a 500 μ M concentration. The sensor, conjugated non‐water soluble polymer 1 (XFPF), merely supports dibutylaniline substituents as binding units. Yet, selective and sensitive detection of Hg 2+ ‐ions is achieved in water. The enhancement in sensory response, when comparing the reference compound 2 to that of 1 in a biphasic system in a microfluidic chip is >10 3 . By manipulation of the structure of 1 , further powerful sensor systems should be easily achieved.