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Lewis Acid Coupled Electron Transfer of Metal–Oxygen Intermediates
Author(s) -
Fukuzumi Shunichi,
Ohkubo Kei,
Lee YongMin,
Nam Wonwoo
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201502693
Subject(s) - chemistry , lewis acids and bases , electron transfer , reactivity (psychology) , redox , bond cleavage , metal , marcus theory , photochemistry , moiety , metal ions in aqueous solution , medicinal chemistry , reaction rate constant , catalysis , inorganic chemistry , stereochemistry , organic chemistry , kinetics , medicine , physics , alternative medicine , pathology , quantum mechanics
Abstract Redox‐inactive metal ions and Brønsted acids that function as Lewis acids play pivotal roles in modulating the redox reactivity of metal–oxygen intermediates, such as metal–oxo and metal–peroxo complexes. The mechanisms of the oxidative CH bond cleavage of toluene derivatives, sulfoxidation of thioanisole derivatives, and epoxidation of styrene derivatives by mononuclear nonheme iron(IV)–oxo complexes in the presence of triflic acid (HOTf) and Sc(OTf) 3 have been unified as rate‐determining electron transfer coupled with binding of Lewis acids (HOTf and Sc(OTf) 3 ) by iron(III)–oxo complexes. All logarithms of the observed second‐order rate constants of Lewis acid‐promoted oxidative CH bond cleavage, sulfoxidation, and epoxidation reactions of iron(IV)–oxo complexes exhibit remarkably unified correlations with the driving forces of proton‐coupled electron transfer (PCET) and metal ion‐coupled electron transfer (MCET) in light of the Marcus theory of electron transfer when the differences in the formation constants of precursor complexes were taken into account. The binding of HOTf and Sc(OTf) 3 to the metal–oxo moiety has been confirmed for Mn IV –oxo complexes. The enhancement of the electron‐transfer reactivity of metal–oxo complexes by binding of Lewis acids increases with increasing the Lewis acidity of redox‐inactive metal ions. Metal ions can also bind to mononuclear nonheme iron(III)–peroxo complexes, resulting in acceleration of the electron‐transfer reduction but deceleration of the electron‐transfer oxidation. Such a control on the reactivity of metal–oxygen intermediates by binding of Lewis acids provides valuable insight into the role of Ca 2+ in the oxidation of water to dioxygen by the oxygen‐evolving complex in photosystem II.

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