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Organoantimony(III)‐Containing Tungstoarsenates(III): From Controlled Assembly to Biological Activity
Author(s) -
Yang Peng,
Bassil Bassem S.,
Lin Zhengguo,
Haider Ali,
AlfaroEspinoza Gabriela,
Ullrich Matthias S.,
Silvestru Cristian,
Kortz Ulrich
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201502398
Subject(s) - thermogravimetric analysis , alkali metal , aqueous solution , chemistry , nuclear chemistry , metal , crystallography , spectroscopy , nuclear magnetic resonance spectroscopy , solid state , stereochemistry , organic chemistry , physics , quantum mechanics
A family of three sandwich‐type, phenylantimony(III)‐containing tungstoarsenates(III), [(PhSb III ){Na(H 2 O)}As III 2 W 19 O 67 (H 2 O)] 11− ( 1 ), [(PhSb III ) 2 As III 2 W 19 O 67 (H 2 O)] 10− ( 2 ), and [(PhSb III ) 3 ( B ‐α‐As III W 9 O 33 ) 2 ] 12− ( 3 ), have been synthesized by one‐pot procedures and isolated as hydrated alkali metal salts, Cs 3 K 3.5 Na 4.5 [(PhSb III ){Na(H 2 O)}As III 2 W 19 O 67 (H 2 O)]⋅41H 2 O ( CsKNa ‐ 1 ), Cs 4.5 K 5.5 [(PhSb III ) 2 As III 2 W 19 O 67 (H 2 O)]⋅35H 2 O ( CsK‐2 ), and Cs 4.5 Na 7.5 [(PhSb III ) 3 ( B ‐α‐As III W 9 O 33 ) 2 ]⋅42H 2 O ( CsNa ‐ 3 ). The number of incorporated {PhSb III } units could be selectively tuned from one to three by careful control of the reaction parameters. The three compounds were characterized in the solid state by single‐crystal XRD, IR spectroscopy, and thermogravimetric analysis. The aqueous solution stability of sandwich polyanions 1 – 3 was also studied by multinuclear ( 1 H, 13 C, 183 W) NMR spectroscopy. Effective inhibitory activity against six different kinds of bacteria was identified for all three polyanions, for which the activity increased with the number of incorporated {PhSb III } groups.