Premium
Selective Interaction of Dopamine with the Self‐Assembled Fibrillar Network of a Molecular Hydrogel Revealed by STD‐NMR
Author(s) -
SegarraMaset María D.,
Escuder Beatriu,
Miravet Juan F.
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201502018
Subject(s) - dopamine , self healing hydrogels , chemistry , materials science , nanotechnology , biophysics , neuroscience , psychology , polymer chemistry , biology
A molecular hydrogel formed by a derivative of L ‐valine with pendant isonicotinoyl moieties interacts selectively with protonated dopamine in the presence of related compounds such as 3‐methylcatechol, and protonated or neutral phenethylamine. A two‐point interaction with the gel fibers is postulated to explain the results. The conclusions are obtained from nuclear magnetic resonance saturation transfer experiments (STD‐NMR), illustrating how this technique is perfectly suited to monitor the interaction of substrates with the fibrillar network of a molecular gel.