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Oxidative Olefination of Anilides with Unactivated Alkenes Catalyzed by an (Electron‐Deficient η 5 ‐Cyclopentadienyl)Rhodium(III) Complex Under Ambient Conditions
Author(s) -
Takahama Yuji,
Shibata Yu,
Tanaka Ken
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201501232
Subject(s) - rhodium , cyclopentadienyl complex , chemistry , catalysis , medicinal chemistry , kinetic isotope effect , oxidative addition , bond cleavage , oxidative phosphorylation , electron , deuterium , stereochemistry , organic chemistry , biochemistry , quantum mechanics , physics
The oxidative olefination of sp 2 CH bonds of anilides with both activated and unactivated alkenes using an (electron‐deficient η 5 ‐cyclopentadienyl)rhodium(III) complex is reported. In contrast to reactions using this electron‐deficient rhodium(III) catalyst, [Cp*RhCl 2 ] 2 showed no activity against olefination with unactivated alkenes. In addition, the deuterium kinetic isotope effect (DKIE) study revealed that the CH bond cleavage step is thought to be the turnover‐limiting step.