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Carboxylate Assisted Ni‐Catalyzed CH Bond Allylation of Benzamides
Author(s) -
Barsu Nagaraju,
Kalsi Deepti,
Sundararaju Basker
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201500639
Subject(s) - catalysis , selectivity , carboxylate , chemistry , solvent , medicinal chemistry , moisture , combinatorial chemistry , organic chemistry
A one‐step synthetic method was developed for allylation of benzamides using Ni(COD) 2 /RCO 2 H and [Ni(μ‐H 2 O)(OOCCMe 3 ) 2 (HOOCCMe 3 ) 2 ] 2 ( A′ ) catalytic system. Efficient, well‐defined, air and moisture‐stable Ni–pivalate complex was isolated and employed in catalytic allylation. The influence of solvent on product selectivity was also investigated.