Comment on “Photochemical Activities of  N ‐Nitroso Carboxamides and Sulfoximides and Their Application to DNA Cleavage” | Zendy

Korth HansGert | Zendy

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Comment on “Photochemical Activities of N ‐Nitroso Carboxamides and Sulfoximides and Their Application to DNA Cleavage”

Author(s) -

Korth HansGert

Publication year - 2021

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201500428

Subject(s) - cleavage (geology) , dna , nitroso , chemistry , electron paramagnetic resonance , nitric oxide , stereochemistry , combinatorial chemistry , presentation (obstetrics) , photochemistry , biochemistry , medicinal chemistry , biology , organic chemistry , physics , medicine , nuclear magnetic resonance , paleontology , fracture (geology) , radiology

This Correspondence reports on a structural and mechanistic misinterpretation of an observed EPR spectrum, a misleading presentation of DNA cleavage data, and the physicochemically unsupported assignment of nitric oxide as a major DNA cleaving agent in the article cited in the title.

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