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Cobalt‐Catalyzed Intermolecular C(sp 2 )O Cross‐Coupling
Author(s) -
Kundu Debasish,
Tripathy Manisha,
Maity Pintu,
Ranu Brindaban C.
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201500058
Subject(s) - transmetalation , aryl , cobalt , catalysis , ligand (biochemistry) , chemistry , halide , intermolecular force , medicinal chemistry , coupling reaction , polymer chemistry , combinatorial chemistry , organic chemistry , molecule , biochemistry , alkyl , receptor
Cobalt(II)‐catalyzed C(sp 2 )O cross‐coupling between aryl/heteroaryl alcohols and vinyl/aryl halides in the presence of Cu I has been achieved under ligand‐free conditions. In this reaction, copper plays a significant role in transmetalation rather than being directly involved in the CO coupling. This unique Co/Cu‐dual catalyst system provides an easy access to a library of aryl–vinyl, heteroaryl–styryl, aryl–aryl, and heteroaryl–heteroaryl ethers in the absence of any ligand or additive.