Premium
Inside Cover: Carboxylate Switch between Hydro‐ and Carbopalladation Pathways in Regiodivergent Dimerization of Alkynes (Chem. Eur. J. 31/2014)
Author(s) -
Zatolochnaya Olga V.,
Gordeev Evgeniy G.,
Jahier Claire,
Ananikov Valentine P.,
Gevorgyan Vladimir
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201490128
Subject(s) - carboxylate , chemistry , regioselectivity , palladium , stereochemistry , head (geology) , medicinal chemistry , catalysis , organic chemistry , geomorphology , geology
As simple as a switch carboxylate anions control the mechanism and hence the regiochemistry of the palladium‐catalyzed dimerization of alkynes. Normally, the kinetically preferred hydropalladation path leads to the head‐to‐head products. In the presence of carboxylate anions, however, this pathway is turned off and the reaction proceeds via carbopalladation to produce head‐to‐tail dimers. For a detailed study, see the Full Paper by V. P. Ananikov, V. Gevorgyan et al. on page 9578 ff.