Premium
Back Cover: Synthesis and Reactivity of New Functionalized Perfluoroalkylfluorophosphates (Chem. Eur. J. 25/2014)
Author(s) -
Allefeld Nadine,
Neumann Beate,
Stammler HansGeorg,
Röschenthaler GerdVolker,
Ignat'ev Nikolai,
Hoge Berthold
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201490102
Subject(s) - chemistry , reagent , nucleophile , aqueous solution , reactivity (psychology) , medicinal chemistry , sodium hydroxide , hydroxide , inorganic chemistry , organic chemistry , catalysis , medicine , alternative medicine , pathology
In this chemical puzzle fluoromethyldimethylamine represents a versatile reactant for the synthesis of electron‐deficient, functionalized phosphates. Thus, the oxidative addition of the reagent to (C 2 F 5 ) n PF 3− n ( n =1–3) selectively affords zwitterionic [(C 2 F 5 ) n F 5− n P(CH 2 NMe 2 CH 2 NMe 2 )] ( n =1–3) in good yields. The course of the reaction involved the phosphoranide [P(C 2 F 5 ) 3 F] − , which was evidenced independently. Treatment of [(C 2 F 5 ) 3 F 2 P(CH 2 NMe 2 CH 2 NMe 2 )] with aqueous sodium hydroxide gave rise to the formation of the phosphate Na + [(C 2 F 5 ) 3 F 2 P(CH 2 NMe 2 )] − . The nucleophilic nitrogen atom in the phosphates [(C 2 F 5 ) n F 5− n P(CH 2 NMe 2 )] − allows the synthesis of several novel functionalized perfluoroalkylfluorophosphates. See the Full Paper by B. Hoge et al. for more details.