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Back Cover: Dormant versus Evolving Aminopalladated Intermediates: Toward a Unified Mechanistic Scenario in Pd II ‐Catalyzed Aminations (Chem. Eur. J. 6/2014)
Author(s) -
Rajabi Jamshid,
Lorion Mélanie M.,
Ly Vu Linh,
Liron Frédéric,
Oble Julie,
Prestat Guillaume,
Poli Giovanni
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201490022
Subject(s) - alkene , allylic rearrangement , reactivity (psychology) , nucleophile , chemistry , catalysis , sigmatropic reaction , medicinal chemistry , stereochemistry , organic chemistry , medicine , alternative medicine , pathology
When an alkene is complexed by PdX 2 in the presence of a nucleophile, the resulting species exhibits a range of competing types of reactivity, such as alkene nucleopalladation or allylic CH activation. In their Full Paper on page 1539 ff., G. Poli et al. show that an initial reversibly formed cyclic aminopalladated intermediate can either evolve along different pathways or stay dormant. In the latter case, alternative types of reactivity, such as allylic CH activation or [3,3]‐sigmatropic rearrangement can predominate.