Frontispiece: Palladium‐Catalysed Direct Cross‐Coupling of Organolithium Reagents with Aryl and Vinyl Triflates

Carbon–Carbon Bond Formation Carbon–carbon bond formation by the cross‐coupling of highly reactive organolithium reagents is a major challenge. Recently, it was demonstrated that palladium catalysts are able to couple organic halides with various organolithium species under mild conditions in a highly selective transformation. In their Communication on page 13078 ff., B. L. Feringa et al. present a catalytic system for the palladium‐catalyzed cross‐coupling of aryl and alkenyl triflates with a range of alkyl and aryllithium reagents. This transformation allows the direct use of organolithium compounds and features short reaction times, thereby providing a viable alternative to current triflate‐based cross‐coupling methodology.