Premium
Synthesis of Small‐Sized, Porous, and Low‐Toxic Magnetite Nanoparticles by Thin POSS Silica Coating
Author(s) -
Yen Swee Kuan,
Varma D. Prathyusha,
Guo Wei Mei,
Ho Vincent H. B.,
Vijayaragavan Vimalan,
Padmanabhan Parasuraman,
Bhakoo Kishore,
Selvan Subramanian Tamil
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201406388
Subject(s) - coating , porosity , magnetite , magnetite nanoparticles , materials science , nanoparticle , chemical engineering , nanotechnology , metallurgy , magnetic nanoparticles , composite material , engineering
Abstract In this communication, we report the synthesis of small‐sized (<10 nm), water‐soluble, magnetic nanoparticles (MNPs) coated with polyhedral oligomeric silsesquioxanes (POSS), which contain either polyethylene glycol (PEG) or octa(tetramethylammonium) (OctaTMA) as functional groups. The POSS‐coated MNPs exhibit superparamagnetic behavior with saturation magnetic moments (51–53 emu g −1 ) comparable to silica‐coated MNPs. They also provide good colloidal stability at different pH and salt concentrations, and low cytotoxicity to MCF‐7 human breast epithelial cells. The relaxivity data and magnetic resonance (MR) phantom images demonstrate the potential application of these MNPs in bioimaging.