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Access to New Endoperoxide Derivatives by Electrochemical Oxidation of Substituted 3‐Azabicyclo[4.1.0]hept‐4‐enes
Author(s) -
Nuter Frédérick,
Dimé Abdou Khadre Djily,
Chen Cheng,
Bounaadja Lotfi,
Mouray Elisabeth,
Florent Isabelle,
Six Yvan,
Buriez Olivier,
Marinetti Angela,
Voituriez Arnaud
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201406138
Subject(s) - cyclic voltammetry , electrochemistry , chemistry , cytotoxicity , combinatorial chemistry , organic chemistry , in vitro , biochemistry , electrode
A series of substituted 3‐azabicyclo[4.1.0]hept‐4‐ene derivatives were prepared and analysed by cyclic voltammetry. Preparative aerobic electrochemical oxidation reactions were then carried out. Three original endoperoxides were isolated, characterised and subjected to antimalarial and cytotoxicity activity assays.