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BODIPY‐Based Fluorescent Thermometer as a Lysosome‐Targetable Probe: How the Oligo(ethylene glycols) Compete Photoinduced Electron Transfer
Author(s) -
Wang Hua,
Wu Yongquan,
Shi Yanlin,
Tao Pan,
Fan Xing,
Su Xinyan,
Kuang GuiChao
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201405853
Subject(s) - bodipy , photoinduced electron transfer , fluorescence , photochemistry , thermometer , ethylene , chemistry , electron transfer , materials science , biochemistry , optics , catalysis , physics , quantum mechanics
A novel BODIPY‐based fluorescent thermometer, which shows a lysosome‐targeting property, was successfully prepared. Due to the electron‐donating ability of the oligo(ethylene glycols), the photoinduced electron‐transfer pathway from morpholine to BODIPY dye is blocked. The fluorescence of the thermometer quenched by intramolecular rotation at room temperature was progressively enhanced during heating due to the increased microviscosity around the fluorophore.