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Rh I ‐Catalyzed Benzo/[7+1] Cycloaddition of Cyclopropyl‐Benzocyclobutenes and CO by Merging Thermal and Metal‐Catalyzed CC Bond Cleavages
Author(s) -
Fu XuFei,
Xiang Yu,
Yu ZhiXiang
Publication year - 2015
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201405712
Subject(s) - cyclopropane , cycloaddition , synthon , catalysis , ring (chemistry) , chemistry , bond cleavage , medicinal chemistry , cleavage (geology) , stereochemistry , metal , organic chemistry , materials science , fracture (geology) , composite material
Abstract A Rh‐catalyzed benzo/[7+1] cycloaddition of cyclopropyl‐benzocyclobutenes (CP‐BCBs) and CO to benzocyclooctenones has been developed. In this reaction, CP‐BCB acts as a benzo/7‐C synthon and the reaction involves two CC bond cleavages: a thermal electrocyclic ring‐opening of the four‐membered ring in CP‐BCB and a Rh‐catalyzed CC cleavage of the cyclopropane ring.