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Metal–Organic Framework‐Derived Copper Nanoparticle@Carbon Nanocomposites as Peroxidase Mimics for Colorimetric Sensing of Ascorbic Acid
Author(s) -
Tan Hongliang,
Ma Chanjiao,
Gao Li,
Li Qian,
Song Yonghai,
Xu Fugang,
Wang Tao,
Wang Li
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201404960
Subject(s) - ascorbic acid , nanocomposite , copper , chemistry , nanoparticle , peroxidase , metal , combinatorial chemistry , horseradish peroxidase , metal organic framework , reducing agent , inorganic chemistry , nuclear chemistry , organic chemistry , nanotechnology , materials science , enzyme , food science , adsorption
Metal–organic frameworks (MOFs) have emerged as very fascinating functional materials due to their diversity nature. A nanocomposite consisting of copper nanoparticles dispersed within a carbon matrix (Cu NPs@C) is prepared through a one‐pot thermolysis of copper‐based metal–organic framework precursors. Cu NPs@C can catalyze the oxidation of 3,3′,5,5′‐tetramethylbenzidine (TMB) to form a colored product in the presence of H 2 O 2 . As a peroxidase mimic, Cu NPs@C not only has the advantages of low cost, high stability, and easy preparation, but also follows Michaelis–Menten behaviors and shows strong affinity to H 2 O 2 . As the Cu NPs’ surfaces are free from stabilizing agent, Cu NPs@C exhibited a higher affinity to H 2 O 2 than horseradish peroxidase. On the basis of the inhibitory effect of ascorbic acid (AA) on oxidation of TMB, this system serves as a colorimetric method for the detection of AA, suggesting that the present work would expand the potential applications of MOF‐derived nanocomposites in biomedical fields.