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Rhodium(III)‐Catalyzed Three‐Component Reaction of Imines, Alkynes, and Aldehydes through CH Activation
Author(s) -
Huang JiRong,
Song Qiang,
Zhu YuQin,
Qin Liu,
Qian ZhiYong,
Dong Lin
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201404576
Subject(s) - rhodium , regioselectivity , catalysis , component (thermodynamics) , tandem , chemistry , combinatorial chemistry , cascade reaction , organic chemistry , materials science , physics , composite material , thermodynamics
An efficient rhodium(III)‐catalyzed tandem three‐component reaction of imines, alkynes and aldehydes through CH activation has been developed. High stereo‐ and regioselectivity, as well as good yields were obtained in most cases. The simple and atom‐economical approach offers a broad scope of substrates, providing polycyclic skeletons with potential biological properties.