Premium
Palladium‐Catalysed Direct Cross‐Coupling of Organolithium Reagents with Aryl and Vinyl Triflates
Author(s) -
Vila Carlos,
Hornillos Valentín,
Giannerini Massimo,
FañanásMastral Martín,
Feringa Ben L.
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201404398
Subject(s) - reagent , aryl , palladium , lithium (medication) , alkyl , coupling reaction , chemistry , organolithium compounds , coupling (piping) , organic chemistry , polymer chemistry , catalysis , materials science , ion , medicine , deprotonation , metallurgy , endocrinology
A palladium‐catalysed cross‐coupling of organolithium reagents with aryl and vinyl triflates is presented. The reaction proceeds at 50 or 70 °C with short reaction times, and the corresponding products are obtained with moderate to high yields, with a variety of alkyl and (hetero)aryl lithium reagents.