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Domino Hydroformylation/Aldol Condensation/Hydrogenation Catalysis: Highly Selective Synthesis of Ketones from Olefins
Author(s) -
Fang Xianjie,
Jackstell Ralf,
Börner Armin,
Beller Matthias
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201404294
Subject(s) - hydroformylation , regioselectivity , chemistry , aldol condensation , organic chemistry , catalysis , aldol reaction , rhodium , domino , phosphine , cascade reaction , olefin fiber
Abstract A general and highly chemo‐ and regioselective synthesis of ketones from olefins by domino hydroformylation/aldol condensation/hydrogenation reaction has been developed. A variety of olefins are efficiently converted into various ketones in good to excellent yields and regioselectivities in the presence of a specific rhodium phosphine/base–acid catalyst system.